Tuesday, July 26, 2005
Two steps forward, one step back: the pleiotropic effects of favoured alleles - describes how much pleiotropy limits the ability of genes to mutate. Pleiotropy is when one gene is involved in multiple different functions. What may be a beneficial change to one function is often deleterious to the rest.
Gene Duplication and the Origin of Novel Proteins - why everything evolutionists thought they knew about gene duplication's role in evolution is wrong.
Simulating evolution by gene duplication of protein features that require multiple amino acid residues - computing the difficulty in obtaining novel, useful proteins with gene duplication.
Evolution at Two Levels: On Genes and Form - a good overview of the modern hypotheses of evolutionary change and benefits and problems of each.
A 21st Century View of Evolution - the genome was not nearly as static as we thought. And hey, those transposons really are useful for something! While Shapiro admits no design, it is hard to read his work and not come away with thinking that there is more than natural law at play here.
These last two freely available on the web, while the others you have to pay for (if anyone finds free links, let me know).